The Calcium Ionised Serum Test measures the biologically active, free calcium ion fraction in the blood, providing a precise assessment of calcium status. Unlike total calcium tests, which include protein-bound calcium, ionized calcium reflects the calcium available for physiological functions such as muscle contraction, nerve transmission, and bone formation. This test is especially important in critically ill patients, those with parathyroid disorders, kidney disease, or conditions affecting blood pH. Abnormal ionized calcium levels can cause symptoms like muscle spasms, tetany, or cardiac arrhythmias. The test is performed using blood samples handled carefully to prevent changes in pH affecting results. Accurate calcium ionized testing improves diagnosis and monitoring of calcium metabolism disorders.
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